A priest from the Vatican is sent in to investigate claims that a small town in Brazil has a church where statues bleed from the eyes. Meanwhile, a young woman in the U.S. begins to show signs of stigmata, the wounds of Christ. The priest from the Vatican links up with her and cares for her as she is increasingly afflicted by the stigmata. Her ranting and raving finally begins to make sense to the priest who starts to question what his religion has stood for for the last 1900 years.
